The PADI2 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to PAD-H19, PAD2, Padi2, and PDI2. This antibody recognizes Human antigen. The PADI2 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a member of the peptidyl arginine
deiminase family of enzymes, which catalyze the post-translational
deimination of proteins by converting arginine residues into
citrullines in the presence of calcium ions. The family members
have distinct substrate specificities and tissue-specific
expression patterns. The type II enzyme is the most widely
expressed family member. Known substrates for this enzyme include
myelin basic protein in the central nervous system and vimentin in
skeletal muscle and macrophages. This enzyme is thought to play a
role in the onset and progression of neurodegenerative human
disorders, including Alzheimer disease and multiple sclerosis, and
it has also been implicated in glaucoma pathogenesis. This gene
exists in a cluster with four other paralogous genes. [provided by
RefSeq]